George Zhang Selected Research

DS-2969b

12/2018	A Phase I, Single-Ascending-Dose Study in Healthy Subjects to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DS-2969b, a Novel GyrB Inhibitor.
1/2018	Phase 1 Study To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Oral Doses of DS-2969b, a Novel GyrB Inhibitor, in Healthy Subjects.

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George Zhang Research Topics

Disease

12	Venous Thromboembolism 04/2019 - 07/2012
8	Neoplasms (Cancer) 01/2022 - 08/2016
8	Hemorrhage 08/2018 - 08/2016
3	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 11/2022 - 12/2021
3	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2021 - 01/2019
3	Pulmonary Embolism 01/2018 - 08/2016
2	Primitive Neuroectodermal Tumors (PNET) 01/2021 - 01/2019
2	Infections 01/2019 - 01/2019
2	Clostridium Infections 12/2018 - 01/2018
2	Body Weight (Weight, Body) 02/2018 - 09/2016
2	Stroke (Strokes) 01/2018 - 10/2013
2	Atrial Fibrillation 01/2018 - 10/2013
2	Embolism (Embolus) 01/2018 - 10/2013
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022
1	Thrombocytosis (Thrombocythemia) 01/2022
1	Anemia 12/2021
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2021
1	Adenocarcinoma 01/2021
1	Inflammation (Inflammations) 01/2020
1	Cystic Fibrosis (Mucoviscidosis) 01/2020
1	Neoplasm Metastasis (Metastasis) 01/2019
1	Multiple Endocrine Neoplasia Type 1 01/2019
1	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 08/2018
1	Angioedema 08/2017
1	Hypertension (High Blood Pressure) 01/2017
1	Right Ventricular Dysfunction 09/2016
1	Venous Thrombosis (Deep-Vein Thrombosis) 08/2016
1	Bladder Exstrophy (Exstrophy, Bladder) 05/2005
1	Prostatic Neoplasms (Prostate Cancer) 03/2002
1	Hyperandrogenism 03/2002
1	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 03/2002
1	Hirsutism 03/2002
1	Hyperinsulinism (Hyperinsulinemia) 03/2002

Drug/Important Bio-Agent (IBA)

12	edoxabanIBA 01/2020 - 07/2012
7	Warfarin (Coumadin)FDA LinkGeneric 04/2019 - 08/2016
5	AnticoagulantsIBA 01/2020 - 08/2016
4	Pharmaceutical PreparationsIBA 08/2017 - 08/2016
3	luspaterceptIBA 11/2022 - 12/2021
3	Dalteparin (Dalteparin Sodium)FDA Link 01/2020 - 02/2018
3	Heparin (Liquaemin)FDA LinkGeneric 01/2018 - 09/2016
3	Factor Xa InhibitorsIBA 01/2018 - 10/2013
2	Hyaluronic Acid (Hyaluronan)IBA 01/2021 - 01/2019
2	Proteins (Proteins, Gene)FDA Link 12/2020 - 01/2019
2	RNA (Ribonucleic Acid)IBA 01/2019 - 05/2005
2	Insulin (Novolin)FDA Link 01/2019 - 03/2002
2	DS-2969bIBA 12/2018 - 01/2018
2	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 02/2018 - 08/2016
2	pro-brain natriuretic peptide (1-76)IBA 01/2018 - 09/2016
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 09/2016 - 08/2016
2	CreatinineIBA 09/2016 - 08/2016
1	osimertinibIBA 01/2022
1	Anaphase-Promoting Complex-CyclosomeIBA 01/2021
1	CytokinesIBA 01/2020
1	lenabasum (ajulemic acid)IBA 01/2020
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 01/2020
1	OilsIBA 01/2019
1	hyaluronan-mediated motility receptorIBA 01/2019
1	oleocanthalIBA 01/2019
1	Olive OilIBA 01/2019
1	Protein Isoforms (Isoforms)IBA 01/2019
1	DNA (Deoxyribonucleic Acid)IBA 01/2019
1	AcidsIBA 01/2019
1	Messenger RNA (mRNA)IBA 01/2019
1	DNA (Cytosine-5-)-Methyltransferase 1IBA 01/2019
1	Cytochrome P-450 CYP2C9IBA 11/2017
1	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2017
1	Histamine Antagonists (Antihistamines)IBA 08/2017
1	Vitamin K FDA Link 01/2017
1	Brain Natriuretic Peptide (Natrecor)FDA Link 09/2016
1	Blood Coagulation Factors (Coagulation Factor)IBA 08/2016
1	Verapamil (Calan)FDA LinkGeneric 08/2016
1	PlacebosIBA 08/2016
1	Quinidine (Chinidin)FDA LinkGeneric 08/2016
1	Enoxaparin (Lovenox)FDA LinkGeneric 07/2012
1	Insulin-Like PeptidesIBA 03/2002
1	Insulin-Like Growth Factor II (Somatomedin A)IBA 03/2002
1	Insulin-Like Growth Factor I (IGF-1)IBA 03/2002
1	Troglitazone (Rezulin)FDA Link 03/2002
1	PPAR-gamma AgonistsIBA 03/2002
1	AndrogensIBA 03/2002

Therapy/Procedure

4	Therapeutics 01/2020 - 01/2017
3	Duration of Therapy 08/2018 - 01/2017
1	Erythrocyte Transfusion 12/2021
1	Wearable Electronic Devices 01/2019
1	Polypharmacy 01/2018
1	Drug Tapering 09/2016